Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.
Identifieur interne : 000321 ( Main/Exploration ); précédent : 000320; suivant : 000322Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.
Auteurs : Xiaoyuan Ren [Suède] ; Lili Zou [Suède, République populaire de Chine] ; Xu Zhang [Suède] ; Vasco Branco [Portugal] ; Jun Wang [République populaire de Chine] ; Cristina Carvalho [Portugal] ; Arne Holmgren [Suède] ; Jun Lu [République populaire de Chine]Source :
- Antioxidants & redox signaling [ 1557-7716 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Glutathione, Reactive Nitrogen Species, Reactive Oxygen Species, Thioredoxins.
- metabolism : Central Nervous System.
- Humans, Oxidation-Reduction, Signal Transduction.
Abstract
SIGNIFICANCE
The thioredoxin (Trx) and glutathione (GSH) systems play important roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress due to its high-energy demand. These two disulfide reductase systems are active in various areas of the brain and are considered to be critical antioxidant systems in the central nervous system (CNS). Various neuronal disorders have been characterized to have imbalanced redox homeostasis. Recent Advances: In addition to their detrimental effects, recent studies have highlighted that reactive oxygen species/reactive nitrogen species (ROS/RNS) act as critical signaling molecules by modifying thiols in proteins. The Trx and GSH systems, which reversibly regulate thiol modifications, regulate redox signaling involved in various biological events in the CNS.
CRITICAL ISSUES
In this review, we focus on the following: (i) how ROS/RNS are produced and mediate signaling in CNS; (ii) how Trx and GSH systems regulate redox signaling by catalyzing reversible thiol modifications; (iii) how dysfunction of the Trx and GSH systems causes alterations of cellular redox signaling in human neuronal diseases; and (iv) the effects of certain small molecules that target thiol-based signaling pathways in the CNS.
FUTURE DIRECTIONS
Further study on the roles of thiol-dependent redox systems in the CNS will improve our understanding of the pathogenesis of many human neuronal disorders and also help to develop novel protective and therapeutic strategies against neuronal diseases. Antioxid. Redox Signal. 27, 989-1010.
DOI: 10.1089/ars.2016.6925
PubMed: 28443683
PubMed Central: PMC5649126
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.</title><author><name sortKey="Ren, Xiaoyuan" sort="Ren, Xiaoyuan" uniqKey="Ren X" first="Xiaoyuan" last="Ren">Xiaoyuan Ren</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zou, Lili" sort="Zou, Lili" uniqKey="Zou L" first="Lili" last="Zou">Lili Zou</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang</wicri:regionArea><wicri:noRegion>Yichang</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xu" sort="Zhang, Xu" uniqKey="Zhang X" first="Xu" last="Zhang">Xu Zhang</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Branco, Vasco" sort="Branco, Vasco" uniqKey="Branco V" first="Vasco" last="Branco">Vasco Branco</name><affiliation wicri:level="1"><nlm:affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jun" sort="Wang, Jun" uniqKey="Wang J" first="Jun" last="Wang">Jun Wang</name><affiliation wicri:level="1"><nlm:affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang</wicri:regionArea><wicri:noRegion>Yichang</wicri:noRegion></affiliation></author><author><name sortKey="Carvalho, Cristina" sort="Carvalho, Cristina" uniqKey="Carvalho C" first="Cristina" last="Carvalho">Cristina Carvalho</name><affiliation wicri:level="1"><nlm:affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Holmgren, Arne" sort="Holmgren, Arne" uniqKey="Holmgren A" first="Arne" last="Holmgren">Arne Holmgren</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Lu, Jun" sort="Lu, Jun" uniqKey="Lu J" first="Jun" last="Lu">Jun Lu</name><affiliation wicri:level="1"><nlm:affiliation>4 School of Pharmaceutical Sciences, Southwest University , Chongqing, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>4 School of Pharmaceutical Sciences, Southwest University , Chongqing</wicri:regionArea><wicri:noRegion>Chongqing</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28443683</idno><idno type="pmid">28443683</idno><idno type="doi">10.1089/ars.2016.6925</idno><idno type="pmc">PMC5649126</idno><idno type="wicri:Area/Main/Corpus">000348</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000348</idno><idno type="wicri:Area/Main/Curation">000348</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000348</idno><idno type="wicri:Area/Main/Exploration">000348</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.</title><author><name sortKey="Ren, Xiaoyuan" sort="Ren, Xiaoyuan" uniqKey="Ren X" first="Xiaoyuan" last="Ren">Xiaoyuan Ren</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zou, Lili" sort="Zou, Lili" uniqKey="Zou L" first="Lili" last="Zou">Lili Zou</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang</wicri:regionArea><wicri:noRegion>Yichang</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xu" sort="Zhang, Xu" uniqKey="Zhang X" first="Xu" last="Zhang">Xu Zhang</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Branco, Vasco" sort="Branco, Vasco" uniqKey="Branco V" first="Vasco" last="Branco">Vasco Branco</name><affiliation wicri:level="1"><nlm:affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jun" sort="Wang, Jun" uniqKey="Wang J" first="Jun" last="Wang">Jun Wang</name><affiliation wicri:level="1"><nlm:affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang</wicri:regionArea><wicri:noRegion>Yichang</wicri:noRegion></affiliation></author><author><name sortKey="Carvalho, Cristina" sort="Carvalho, Cristina" uniqKey="Carvalho C" first="Cristina" last="Carvalho">Cristina Carvalho</name><affiliation wicri:level="1"><nlm:affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Holmgren, Arne" sort="Holmgren, Arne" uniqKey="Holmgren A" first="Arne" last="Holmgren">Arne Holmgren</name><affiliation wicri:level="3"><nlm:affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Lu, Jun" sort="Lu, Jun" uniqKey="Lu J" first="Jun" last="Lu">Jun Lu</name><affiliation wicri:level="1"><nlm:affiliation>4 School of Pharmaceutical Sciences, Southwest University , Chongqing, China .</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>4 School of Pharmaceutical Sciences, Southwest University , Chongqing</wicri:regionArea><wicri:noRegion>Chongqing</wicri:noRegion></affiliation></author></analytic><series><title level="j">Antioxidants & redox signaling</title><idno type="eISSN">1557-7716</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Central Nervous System (metabolism)</term><term>Glutathione (metabolism)</term><term>Humans (MeSH)</term><term>Oxidation-Reduction (MeSH)</term><term>Reactive Nitrogen Species (metabolism)</term><term>Reactive Oxygen Species (metabolism)</term><term>Signal Transduction (MeSH)</term><term>Thioredoxins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Espèces réactives de l'azote (métabolisme)</term><term>Espèces réactives de l'oxygène (métabolisme)</term><term>Glutathion (métabolisme)</term><term>Humains (MeSH)</term><term>Oxydoréduction (MeSH)</term><term>Système nerveux central (métabolisme)</term><term>Thiorédoxines (métabolisme)</term><term>Transduction du signal (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glutathione</term><term>Reactive Nitrogen Species</term><term>Reactive Oxygen Species</term><term>Thioredoxins</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Central Nervous System</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Espèces réactives de l'azote</term><term>Espèces réactives de l'oxygène</term><term>Glutathion</term><term>Système nerveux central</term><term>Thiorédoxines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Oxidation-Reduction</term><term>Signal Transduction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Oxydoréduction</term><term>Transduction du signal</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>SIGNIFICANCE</b></p><p>The thioredoxin (Trx) and glutathione (GSH) systems play important roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress due to its high-energy demand. These two disulfide reductase systems are active in various areas of the brain and are considered to be critical antioxidant systems in the central nervous system (CNS). Various neuronal disorders have been characterized to have imbalanced redox homeostasis. Recent Advances: In addition to their detrimental effects, recent studies have highlighted that reactive oxygen species/reactive nitrogen species (ROS/RNS) act as critical signaling molecules by modifying thiols in proteins. The Trx and GSH systems, which reversibly regulate thiol modifications, regulate redox signaling involved in various biological events in the CNS.</p></div><div type="abstract" xml:lang="en"><p><b>CRITICAL ISSUES</b></p><p>In this review, we focus on the following: (i) how ROS/RNS are produced and mediate signaling in CNS; (ii) how Trx and GSH systems regulate redox signaling by catalyzing reversible thiol modifications; (iii) how dysfunction of the Trx and GSH systems causes alterations of cellular redox signaling in human neuronal diseases; and (iv) the effects of certain small molecules that target thiol-based signaling pathways in the CNS.</p></div><div type="abstract" xml:lang="en"><p><b>FUTURE DIRECTIONS</b></p><p>Further study on the roles of thiol-dependent redox systems in the CNS will improve our understanding of the pathogenesis of many human neuronal disorders and also help to develop novel protective and therapeutic strategies against neuronal diseases. Antioxid. Redox Signal. 27, 989-1010.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28443683</PMID><DateCompleted><Year>2018</Year><Month>03</Month><Day>09</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1557-7716</ISSN><JournalIssue CitedMedium="Internet"><Volume>27</Volume><Issue>13</Issue><PubDate><Year>2017</Year><Month>Nov</Month><Day>01</Day></PubDate></JournalIssue><Title>Antioxidants & redox signaling</Title><ISOAbbreviation>Antioxid Redox Signal</ISOAbbreviation></Journal><ArticleTitle>Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.</ArticleTitle><Pagination><MedlinePgn>989-1010</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1089/ars.2016.6925</ELocationID><Abstract><AbstractText Label="SIGNIFICANCE" NlmCategory="CONCLUSIONS">The thioredoxin (Trx) and glutathione (GSH) systems play important roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress due to its high-energy demand. These two disulfide reductase systems are active in various areas of the brain and are considered to be critical antioxidant systems in the central nervous system (CNS). Various neuronal disorders have been characterized to have imbalanced redox homeostasis. Recent Advances: In addition to their detrimental effects, recent studies have highlighted that reactive oxygen species/reactive nitrogen species (ROS/RNS) act as critical signaling molecules by modifying thiols in proteins. The Trx and GSH systems, which reversibly regulate thiol modifications, regulate redox signaling involved in various biological events in the CNS.</AbstractText><AbstractText Label="CRITICAL ISSUES" NlmCategory="RESULTS">In this review, we focus on the following: (i) how ROS/RNS are produced and mediate signaling in CNS; (ii) how Trx and GSH systems regulate redox signaling by catalyzing reversible thiol modifications; (iii) how dysfunction of the Trx and GSH systems causes alterations of cellular redox signaling in human neuronal diseases; and (iv) the effects of certain small molecules that target thiol-based signaling pathways in the CNS.</AbstractText><AbstractText Label="FUTURE DIRECTIONS" NlmCategory="CONCLUSIONS">Further study on the roles of thiol-dependent redox systems in the CNS will improve our understanding of the pathogenesis of many human neuronal disorders and also help to develop novel protective and therapeutic strategies against neuronal diseases. Antioxid. Redox Signal. 27, 989-1010.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ren</LastName><ForeName>Xiaoyuan</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zou</LastName><ForeName>Lili</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xu</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Branco</LastName><ForeName>Vasco</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>2 Translational Neuroscience and Neural Regeneration and Repair Institute/Institute of Cell Therapy, The First Hospital of Yichang, Three Gorges University , Yichang, China .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carvalho</LastName><ForeName>Cristina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>3 Research Institute for Medicines (iMed.ULisboa) , Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holmgren</LastName><ForeName>Arne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>1 Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet , Stockholm, Sweden .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>4 School of Pharmaceutical Sciences, Southwest University , Chongqing, China .</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Antioxid Redox Signal</MedlineTA><NlmUniqueID>100888899</NlmUniqueID><ISSNLinking>1523-0864</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D026361">Reactive Nitrogen Species</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017382">Reactive Oxygen Species</NameOfSubstance></Chemical><Chemical><RegistryNumber>52500-60-4</RegistryNumber><NameOfSubstance UI="D013879">Thioredoxins</NameOfSubstance></Chemical><Chemical><RegistryNumber>GAN16C9B8O</RegistryNumber><NameOfSubstance UI="D005978">Glutathione</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002490" MajorTopicYN="N">Central Nervous System</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005978" MajorTopicYN="N">Glutathione</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010084" MajorTopicYN="N">Oxidation-Reduction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D026361" MajorTopicYN="N">Reactive Nitrogen Species</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017382" MajorTopicYN="N">Reactive Oxygen Species</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013879" MajorTopicYN="N">Thioredoxins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">CNS</Keyword><Keyword MajorTopicYN="N">glutaredoxin</Keyword><Keyword MajorTopicYN="N">glutathione</Keyword><Keyword MajorTopicYN="N">redox signaling</Keyword><Keyword MajorTopicYN="N">thiol-targeted compounds</Keyword><Keyword MajorTopicYN="N">thioredoxin</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>3</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28443683</ArticleId><ArticleId IdType="doi">10.1089/ars.2016.6925</ArticleId><ArticleId IdType="pmc">PMC5649126</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>J Biol Chem. 2008 Aug 8;283(32):21890-8</Citation><ArticleIdList><ArticleId IdType="pubmed">18544525</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2004 Nov 15;201(1):21-31</Citation><ArticleIdList><ArticleId IdType="pubmed">15519605</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicology. 2001 May 11;162(2):81-8</Citation><ArticleIdList><ArticleId IdType="pubmed">11337108</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2010 Dec 1;49(11):1617-28</Citation><ArticleIdList><ArticleId IdType="pubmed">20851762</ArticleId></ArticleIdList></Reference><Reference><Citation>Neuron. 1989 Oct;3(4):519-26</Citation><ArticleIdList><ArticleId IdType="pubmed">2484340</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 1997 Sep 29;238(3):703-6</Citation><ArticleIdList><ArticleId IdType="pubmed">9325152</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol In Vitro. 2007 Apr;21(3):355-63</Citation><ArticleIdList><ArticleId IdType="pubmed">17055214</ArticleId></ArticleIdList></Reference><Reference><Citation>Psychopharmacology (Berl). 2016 Mar;233(6):1097-104</Citation><ArticleIdList><ArticleId IdType="pubmed">26758281</ArticleId></ArticleIdList></Reference><Reference><Citation>Sci Signal. 2009 Nov 10;2(96):ra72</Citation><ArticleIdList><ArticleId IdType="pubmed">19903941</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2003 May 1;371(Pt 3):743-52</Citation><ArticleIdList><ArticleId IdType="pubmed">12556226</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18742-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18003920</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurosci Res. 1999 Nov 1;58(3):436-41</Citation><ArticleIdList><ArticleId IdType="pubmed">10518117</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10810-4</Citation><ArticleIdList><ArticleId IdType="pubmed">15252205</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Neurosci. 2008 Apr;11(4):476-87</Citation><ArticleIdList><ArticleId IdType="pubmed">18344994</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2011 Mar 1;251(2):95-103</Citation><ArticleIdList><ArticleId IdType="pubmed">21168431</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2007 Sep 7;282(36):26562-74</Citation><ArticleIdList><ArticleId IdType="pubmed">17613523</ArticleId></ArticleIdList></Reference><Reference><Citation>Prog Neurobiol. 2000 Dec;62(6):649-71</Citation><ArticleIdList><ArticleId IdType="pubmed">10880854</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 2003 Jun 27;976(2):243-52</Citation><ArticleIdList><ArticleId IdType="pubmed">12763259</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 1998 Apr 21;37(16):5383-93</Citation><ArticleIdList><ArticleId IdType="pubmed">9548920</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2004 Nov 12;279(46):47939-51</Citation><ArticleIdList><ArticleId IdType="pubmed">15347644</ArticleId></ArticleIdList></Reference><Reference><Citation>Stroke. 2013 Apr;44(4):1124-34</Citation><ArticleIdList><ArticleId IdType="pubmed">23429506</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 2009 Mar 9;1259:74-9</Citation><ArticleIdList><ArticleId IdType="pubmed">19135428</ArticleId></ArticleIdList></Reference><Reference><Citation>Biol Trace Elem Res. 2015 May;165(1):67-74</Citation><ArticleIdList><ArticleId IdType="pubmed">25613582</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Mol Sci. 2012;13(9):12017-35</Citation><ArticleIdList><ArticleId IdType="pubmed">23109897</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2003 May 30;278(22):19603-10</Citation><ArticleIdList><ArticleId IdType="pubmed">12649289</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Lett. 2010 Dec 15;199(3):239-46</Citation><ArticleIdList><ArticleId IdType="pubmed">20851755</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2012 Jan 13;45(1):13-24</Citation><ArticleIdList><ArticleId IdType="pubmed">22244329</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurochem Int. 2007 Jul;51(1):37-46</Citation><ArticleIdList><ArticleId IdType="pubmed">17512091</ArticleId></ArticleIdList></Reference><Reference><Citation>J Inherit Metab Dis. 2013 Jan;36(1):63-73</Citation><ArticleIdList><ArticleId IdType="pubmed">22767283</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):243-70</Citation><ArticleIdList><ArticleId IdType="pubmed">16677071</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Neurol. 1987 Apr;21(4):331-6</Citation><ArticleIdList><ArticleId IdType="pubmed">3579218</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2002 Sep 1;33(5):627-38</Citation><ArticleIdList><ArticleId IdType="pubmed">12208349</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2007 Feb 6;46(5):1219-27</Citation><ArticleIdList><ArticleId IdType="pubmed">17260951</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2013 Nov 8;288(45):32241-7</Citation><ArticleIdList><ArticleId IdType="pubmed">24062305</ArticleId></ArticleIdList></Reference><Reference><Citation>Nitric Oxide. 2011 Aug 1;25(2):161-8</Citation><ArticleIdList><ArticleId IdType="pubmed">21703357</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Calcium. 2007 May;41(5):491-502</Citation><ArticleIdList><ArticleId IdType="pubmed">17074386</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Mol Med. 2010 Mar;14(3):457-87</Citation><ArticleIdList><ArticleId IdType="pubmed">20070435</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Biochem. 1985;54:237-71</Citation><ArticleIdList><ArticleId IdType="pubmed">3896121</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Neurosci. 2006 Apr;7(4):278-94</Citation><ArticleIdList><ArticleId IdType="pubmed">16552414</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurobiol Dis. 2000 Feb;7(1):23-37</Citation><ArticleIdList><ArticleId IdType="pubmed">10671320</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurosci Lett. 2001 Nov 27;315(3):149-53</Citation><ArticleIdList><ArticleId IdType="pubmed">11716985</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(11):e50683</Citation><ArticleIdList><ArticleId IdType="pubmed">23226354</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Chem Biol. 2005 Aug;1(3):154-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16408020</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2012 Feb 15;52(4):781-93</Citation><ArticleIdList><ArticleId IdType="pubmed">22198265</ArticleId></ArticleIdList></Reference><Reference><Citation>Hum Mol Genet. 2015 Mar 1;24(5):1322-35</Citation><ArticleIdList><ArticleId IdType="pubmed">25355420</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 1964 Oct;239:3436-44</Citation><ArticleIdList><ArticleId IdType="pubmed">14245400</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Neurosci. 2008 Jun;27(11):2783-802</Citation><ArticleIdList><ArticleId IdType="pubmed">18588525</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8</Citation><ArticleIdList><ArticleId IdType="pubmed">11481439</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2005 Apr 15;280(15):14453-61</Citation><ArticleIdList><ArticleId IdType="pubmed">15684422</ArticleId></ArticleIdList></Reference><Reference><Citation>Biol Chem. 1997 Aug;378(8):793-802</Citation><ArticleIdList><ArticleId IdType="pubmed">9377474</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2007 Apr 13;26(1):63-74</Citation><ArticleIdList><ArticleId IdType="pubmed">17434127</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2010 Feb 19;140(4):517-28</Citation><ArticleIdList><ArticleId IdType="pubmed">20178744</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 2011 Jan;25(1):370-81</Citation><ArticleIdList><ArticleId IdType="pubmed">20810785</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10480-4</Citation><ArticleIdList><ArticleId IdType="pubmed">1720542</ArticleId></ArticleIdList></Reference><Reference><Citation>Microsc Res Tech. 2005 Jul;67(3-4):156-63</Citation><ArticleIdList><ArticleId IdType="pubmed">16104002</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Res. 2014 Jun;48(6):623-40</Citation><ArticleIdList><ArticleId IdType="pubmed">24593876</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 1999 Mar 27;823(1-2):1-10</Citation><ArticleIdList><ArticleId IdType="pubmed">10095006</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 1982 Dec 21;21(26):6628-33</Citation><ArticleIdList><ArticleId IdType="pubmed">7159551</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2014 Aug;73:95-105</Citation><ArticleIdList><ArticleId IdType="pubmed">24816296</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2009 Apr 3;324(5923):102-5</Citation><ArticleIdList><ArticleId IdType="pubmed">19342591</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicology. 2007 May 20;234(3):145-56</Citation><ArticleIdList><ArticleId IdType="pubmed">17408840</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2008 May 2;283(18):11913-23</Citation><ArticleIdList><ArticleId IdType="pubmed">18321861</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurochem. 1980 Jun;34(6):1421-8</Citation><ArticleIdList><ArticleId IdType="pubmed">7381468</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 2003 Aug 14;549(1-3):105-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12914934</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2012 Oct 1;447(1):167-74</Citation><ArticleIdList><ArticleId IdType="pubmed">22784015</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2006 Oct 19;443(7113):787-95</Citation><ArticleIdList><ArticleId IdType="pubmed">17051205</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurobiol Dis. 2005 Apr;18(3):618-27</Citation><ArticleIdList><ArticleId IdType="pubmed">15755687</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2001 Jul 13;276(28):26269-75</Citation><ArticleIdList><ArticleId IdType="pubmed">11297543</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Metab. 2012 Aug 8;16(2):265-73</Citation><ArticleIdList><ArticleId IdType="pubmed">22883234</ArticleId></ArticleIdList></Reference><Reference><Citation>J Alzheimers Dis. 2014;39(4):787-97</Citation><ArticleIdList><ArticleId IdType="pubmed">24270206</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2014 Jan;66:75-87</Citation><ArticleIdList><ArticleId IdType="pubmed">23899494</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2009 May 20;28(10 ):1505-17</Citation><ArticleIdList><ArticleId IdType="pubmed">19369943</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 1999 Sep;27(5-6):588-95</Citation><ArticleIdList><ArticleId IdType="pubmed">10490279</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2009 Dec 23;425(2):313-25</Citation><ArticleIdList><ArticleId IdType="pubmed">20025614</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Commun. 2014;5:2958</Citation><ArticleIdList><ArticleId IdType="pubmed">24389582</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 1997 May 19;234(2):293-5</Citation><ArticleIdList><ArticleId IdType="pubmed">9177261</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2009 Nov 13;284(46):31532-40</Citation><ArticleIdList><ArticleId IdType="pubmed">19755417</ArticleId></ArticleIdList></Reference><Reference><Citation>Semin Cell Dev Biol. 2015 Jan;37:66-72</Citation><ArticleIdList><ArticleId IdType="pubmed">25263013</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2007 Oct 19;282(42):30667-72</Citation><ArticleIdList><ArticleId IdType="pubmed">17720813</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 2009 Aug;23(8):2394-402</Citation><ArticleIdList><ArticleId IdType="pubmed">19351701</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2005 May 19;435(7040):347-53</Citation><ArticleIdList><ArticleId IdType="pubmed">15902258</ArticleId></ArticleIdList></Reference><Reference><Citation>Postepy Hig Med Dosw (Online). 2005;59:464-71</Citation><ArticleIdList><ArticleId IdType="pubmed">16258411</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2004 Feb 27;279(9):7537-43</Citation><ArticleIdList><ArticleId IdType="pubmed">14676218</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Neurosci. 2002 Sep;25(9):474-80</Citation><ArticleIdList><ArticleId IdType="pubmed">12183209</ArticleId></ArticleIdList></Reference><Reference><Citation>J Bioenerg Biomembr. 2014 Dec;46(6):471-7</Citation><ArticleIdList><ArticleId IdType="pubmed">25248416</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2005 Dec 23;338(3):1547-50</Citation><ArticleIdList><ArticleId IdType="pubmed">16274669</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 2003 Apr;17(6):717-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12594173</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2005 Mar 18;280(11):10846-54</Citation><ArticleIdList><ArticleId IdType="pubmed">15653693</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 2003 Mar 28;967(1-2):152-60</Citation><ArticleIdList><ArticleId IdType="pubmed">12650976</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2014 Aug 10;21(5):669-81</Citation><ArticleIdList><ArticleId IdType="pubmed">24295294</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2011 Nov 1;256(3):405-17</Citation><ArticleIdList><ArticleId IdType="pubmed">21601588</ArticleId></ArticleIdList></Reference><Reference><Citation>Oxid Med Cell Longev. 2014;2014:590808</Citation><ArticleIdList><ArticleId IdType="pubmed">24723994</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurosci Lett. 1997 Nov 7;236(3):139-42</Citation><ArticleIdList><ArticleId IdType="pubmed">9406756</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2008 Nov;10(11):1941-88</Citation><ArticleIdList><ArticleId IdType="pubmed">18774901</ArticleId></ArticleIdList></Reference><Reference><Citation>Cold Spring Harb Symp Quant Biol. 1991;56:265-73</Citation><ArticleIdList><ArticleId IdType="pubmed">1819490</ArticleId></ArticleIdList></Reference><Reference><Citation>Environ Health Perspect. 2005 Aug;113(8):1015-21</Citation><ArticleIdList><ArticleId IdType="pubmed">16079072</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 2004 Jun 18;1011(2):170-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15157803</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 1995 Oct 13;270(5234):296-9</Citation><ArticleIdList><ArticleId IdType="pubmed">7569979</ArticleId></ArticleIdList></Reference><Reference><Citation>Comp Biochem Physiol B Biochem Mol Biol. 2012 Feb;161(2):134-9</Citation><ArticleIdList><ArticleId IdType="pubmed">22056681</ArticleId></ArticleIdList></Reference><Reference><Citation>Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:134-44</Citation><ArticleIdList><ArticleId IdType="pubmed">26348786</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurochem Res. 2009 Apr;34(4):727-33</Citation><ArticleIdList><ArticleId IdType="pubmed">19199029</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Dis. 2013 Aug 15;4:e771</Citation><ArticleIdList><ArticleId IdType="pubmed">23949220</ArticleId></ArticleIdList></Reference><Reference><Citation>Brain Res. 2009 Jul 24;1281:101-7</Citation><ArticleIdList><ArticleId IdType="pubmed">19464274</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurosci Res. 2007 May 15;85(7):1506-14</Citation><ArticleIdList><ArticleId IdType="pubmed">17387692</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 1999 May 18;38(20):6699-705</Citation><ArticleIdList><ArticleId IdType="pubmed">10350489</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 2001 Jun;15(8):1425-7</Citation><ArticleIdList><ArticleId IdType="pubmed">11387245</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicology. 2006 Jun 15;223(3):181-90</Citation><ArticleIdList><ArticleId IdType="pubmed">16713667</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 1999 Jul 30;274(31):21645-50</Citation><ArticleIdList><ArticleId IdType="pubmed">10419473</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Rep. 2014 Sep 25;8(6):1870-1878</Citation><ArticleIdList><ArticleId IdType="pubmed">25220457</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2007 Jul;9(7):775-806</Citation><ArticleIdList><ArticleId IdType="pubmed">17508906</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2008 Jan 25;283(4):2427-38</Citation><ArticleIdList><ArticleId IdType="pubmed">18032379</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17385-90</Citation><ArticleIdList><ArticleId IdType="pubmed">20855618</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 1998 Jun 19;273(25):15366-72</Citation><ArticleIdList><ArticleId IdType="pubmed">9624118</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1865-79</Citation><ArticleIdList><ArticleId IdType="pubmed">16987039</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Immunol. 2001 Oct;2(10):907-16</Citation><ArticleIdList><ArticleId IdType="pubmed">11577346</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 2010 Aug 4;584(15):3398-401</Citation><ArticleIdList><ArticleId IdType="pubmed">20600005</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Rep. 2015 Nov 30;5:27-34</Citation><ArticleIdList><ArticleId IdType="pubmed">28955804</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 2002 Jun 1;16(11):1345-55</Citation><ArticleIdList><ArticleId IdType="pubmed">12050113</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2005 Oct;115(10 ):2656-64</Citation><ArticleIdList><ArticleId IdType="pubmed">16200199</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Neurol. 1994 Sep;36(3):356-61</Citation><ArticleIdList><ArticleId IdType="pubmed">8080243</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 Dec 24;285(52):40699-705</Citation><ArticleIdList><ArticleId IdType="pubmed">20929858</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry (Mosc). 2015 May;80(5):517-31</Citation><ArticleIdList><ArticleId IdType="pubmed">26071769</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 1994 Feb;124(2):221-9</Citation><ArticleIdList><ArticleId IdType="pubmed">8122267</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2011 Jan;1810(1):93-110</Citation><ArticleIdList><ArticleId IdType="pubmed">20620191</ArticleId></ArticleIdList></Reference><Reference><Citation>Glia. 2011 May;59(5):810-20</Citation><ArticleIdList><ArticleId IdType="pubmed">21351162</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2012 Nov 2;287(45):38210-9</Citation><ArticleIdList><ArticleId IdType="pubmed">22977247</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Neurosci. 2014 Dec;15(12):771-85</Citation><ArticleIdList><ArticleId IdType="pubmed">25387473</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Mol Cell Biol. 2009 Oct;10 (10 ):721-32</Citation><ArticleIdList><ArticleId IdType="pubmed">19738628</ArticleId></ArticleIdList></Reference><Reference><Citation>Oxid Med Cell Longev. 2016;2016:6143753</Citation><ArticleIdList><ArticleId IdType="pubmed">26989453</ArticleId></ArticleIdList></Reference><Reference><Citation>Structure. 1995 Mar 15;3(3):245-50</Citation><ArticleIdList><ArticleId IdType="pubmed">7788290</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2007 May 11;282(19):14186-93</Citation><ArticleIdList><ArticleId IdType="pubmed">17389593</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Cell Biol. 2005 Jul;7(7):665-74</Citation><ArticleIdList><ArticleId IdType="pubmed">15951807</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurochem. 1999 Jun;72(6):2523-30</Citation><ArticleIdList><ArticleId IdType="pubmed">10349863</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2016 Feb 25;12(2):e1005442</Citation><ArticleIdList><ArticleId IdType="pubmed">26915097</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2000 Feb 1;28(3):418-27</Citation><ArticleIdList><ArticleId IdType="pubmed">10699754</ArticleId></ArticleIdList></Reference><Reference><Citation>J Proteomics. 2011 Oct 19;74(11):2498-509</Citation><ArticleIdList><ArticleId IdType="pubmed">21704743</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Proteomics. 2010 Oct;9(10):2262-75</Citation><ArticleIdList><ArticleId IdType="pubmed">20660346</ArticleId></ArticleIdList></Reference><Reference><Citation>J Pharmacol Sci. 2008 Nov;108(3):227-38</Citation><ArticleIdList><ArticleId IdType="pubmed">19008644</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2014 May 30;289(22):15611-20</Citation><ArticleIdList><ArticleId IdType="pubmed">24722990</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurotoxicology. 2006 Jul;27(4):492-500</Citation><ArticleIdList><ArticleId IdType="pubmed">16513172</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2008 May 23;320(5879):1050-4</Citation><ArticleIdList><ArticleId IdType="pubmed">18497292</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Cell Biol. 2002 Oct;4(10):743-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12244325</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Mol Cell Biol. 2001 Jul;2(7):550-6</Citation><ArticleIdList><ArticleId IdType="pubmed">11433370</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2009 Mar 24;106(12 ):4900-5</Citation><ArticleIdList><ArticleId IdType="pubmed">19273858</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2014 Dec 18;56(6):786-95</Citation><ArticleIdList><ArticleId IdType="pubmed">25435139</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Biochem Biophys. 1992 Jun;295(2):230-4</Citation><ArticleIdList><ArticleId IdType="pubmed">1586151</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2007 Mar 16;282(11):7939-49</Citation><ArticleIdList><ArticleId IdType="pubmed">17229725</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2002 Aug;4(4):693-6</Citation><ArticleIdList><ArticleId IdType="pubmed">12230882</ArticleId></ArticleIdList></Reference><Reference><Citation>J Trace Elem Med Biol. 2015;31:157-62</Citation><ArticleIdList><ArticleId IdType="pubmed">25511910</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2003 Jan 24;278(4):2141-6</Citation><ArticleIdList><ArticleId IdType="pubmed">12435734</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2016 Apr;93:110-7</Citation><ArticleIdList><ArticleId IdType="pubmed">26845616</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2009 Nov;1790(11):1471-7</Citation><ArticleIdList><ArticleId IdType="pubmed">19406207</ArticleId></ArticleIdList></Reference><Reference><Citation>Chem Sci. 2016 May 25;7(5):3414-3426</Citation><ArticleIdList><ArticleId IdType="pubmed">27170841</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2007 Jan 1;42(1):118-23</Citation><ArticleIdList><ArticleId IdType="pubmed">17157198</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Cardiol. 2013 Sep 1;167(5):1860-6</Citation><ArticleIdList><ArticleId IdType="pubmed">22626835</ArticleId></ArticleIdList></Reference><Reference><Citation>Crit Rev Toxicol. 2006 Sep;36(8):609-62</Citation><ArticleIdList><ArticleId IdType="pubmed">16973445</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15774-9</Citation><ArticleIdList><ArticleId IdType="pubmed">20798033</ArticleId></ArticleIdList></Reference><Reference><Citation>Biometals. 2013 Oct;26(5):763-71</Citation><ArticleIdList><ArticleId IdType="pubmed">23839117</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA Neurol. 2014 May;71(5):543-52</Citation><ArticleIdList><ArticleId IdType="pubmed">24664227</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2006 Nov 3;281(44):33107-14</Citation><ArticleIdList><ArticleId IdType="pubmed">16956877</ArticleId></ArticleIdList></Reference><Reference><Citation>Mech Ageing Dev. 1986-1987 Jan;37(3):183-95</Citation><ArticleIdList><ArticleId IdType="pubmed">3106727</ArticleId></ArticleIdList></Reference><Reference><Citation>FASEB J. 1998 Jul;12(10):773-90</Citation><ArticleIdList><ArticleId IdType="pubmed">9657518</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Differ. 2006 Sep;13(9):1454-65</Citation><ArticleIdList><ArticleId IdType="pubmed">16311508</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurochem Res. 2004 Mar;29(3):569-77</Citation><ArticleIdList><ArticleId IdType="pubmed">15038604</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Sci. 2011 Aug;122(2):551-6</Citation><ArticleIdList><ArticleId IdType="pubmed">21546347</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Biochem Biophys. 1996 Dec 1;336(1):113-20</Citation><ArticleIdList><ArticleId IdType="pubmed">8951041</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2009 Jan 9;284(2):723-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18757362</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2006 May 25;441(7092):513-7</Citation><ArticleIdList><ArticleId IdType="pubmed">16724068</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Biochem. 2000 Aug;267(16):4904-11</Citation><ArticleIdList><ArticleId IdType="pubmed">10931172</ArticleId></ArticleIdList></Reference><Reference><Citation>Mov Disord. 2010 Sep 15;25(12):1924-8</Citation><ArticleIdList><ArticleId IdType="pubmed">20669312</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2010 May 21;396(1):120-4</Citation><ArticleIdList><ArticleId IdType="pubmed">20494123</ArticleId></ArticleIdList></Reference><Reference><Citation>Sci Adv. 2016 Jan 22;2(1):e1500968</Citation><ArticleIdList><ArticleId IdType="pubmed">26844296</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicology. 2012 Dec 8;302(1):60-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22885222</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2011 Jul 8;43(1):19-32</Citation><ArticleIdList><ArticleId IdType="pubmed">21726807</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2016 Aug 16;55(32):4519-32</Citation><ArticleIdList><ArticleId IdType="pubmed">26894491</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2002 Jan 15;178(2):82-92</Citation><ArticleIdList><ArticleId IdType="pubmed">11814328</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2013 May 20;18(15):1906-19</Citation><ArticleIdList><ArticleId IdType="pubmed">23176571</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurochem. 2006 Jun;97(6):1634-58</Citation><ArticleIdList><ArticleId IdType="pubmed">16805774</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 Sep 3;285(36):27850-8</Citation><ArticleIdList><ArticleId IdType="pubmed">20558743</ArticleId></ArticleIdList></Reference><Reference><Citation>Chem Res Toxicol. 2011 Apr 18;24(4):434-50</Citation><ArticleIdList><ArticleId IdType="pubmed">21391663</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2016 Feb 5;291(6):3053-62</Citation><ArticleIdList><ArticleId IdType="pubmed">26601956</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2010 Jun 15;12(12):1339-53</Citation><ArticleIdList><ArticleId IdType="pubmed">19938943</ArticleId></ArticleIdList></Reference><Reference><Citation>Exp Toxicol Pathol. 2012 Jul;64(5):431-4</Citation><ArticleIdList><ArticleId IdType="pubmed">21130632</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2003 Oct 24;278(43):42588-95</Citation><ArticleIdList><ArticleId IdType="pubmed">12915401</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS J. 2013 Jan;280(2):708-30</Citation><ArticleIdList><ArticleId IdType="pubmed">22938156</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Biochem. 2010 Jan 14;11:3</Citation><ArticleIdList><ArticleId IdType="pubmed">20074363</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Sci. 2011 Jun;121(2):368-75</Citation><ArticleIdList><ArticleId IdType="pubmed">21402726</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2007 Jul 3;46(26):7765-80</Citation><ArticleIdList><ArticleId IdType="pubmed">17555331</ArticleId></ArticleIdList></Reference><Reference><Citation>Stroke. 1998 Jan;29(1):12-7</Citation><ArticleIdList><ArticleId IdType="pubmed">9445321</ArticleId></ArticleIdList></Reference><Reference><Citation>Neurotox Res. 2014 Jul;26(1):40-51</Citation><ArticleIdList><ArticleId IdType="pubmed">24519665</ArticleId></ArticleIdList></Reference><Reference><Citation>Circ Res. 2004 Jun 11;94(11):1483-91</Citation><ArticleIdList><ArticleId IdType="pubmed">15117824</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurosci Res. 1999 Apr 15;56(2):206-12</Citation><ArticleIdList><ArticleId IdType="pubmed">10494109</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2011 Nov 1;439(3):479-85</Citation><ArticleIdList><ArticleId IdType="pubmed">21732914</ArticleId></ArticleIdList></Reference><Reference><Citation>Neuroimmunomodulation. 2014;21(1):13-20</Citation><ArticleIdList><ArticleId IdType="pubmed">24135853</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2015 Aug 1;286(3):216-23</Citation><ArticleIdList><ArticleId IdType="pubmed">25981166</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2012 Sep 1;17(5):719-32</Citation><ArticleIdList><ArticleId IdType="pubmed">22356734</ArticleId></ArticleIdList></Reference><Reference><Citation>Neuropsychopharmacology. 2001 Apr;24(4):420-9</Citation><ArticleIdList><ArticleId IdType="pubmed">11182537</ArticleId></ArticleIdList></Reference><Reference><Citation>Sci Signal. 2011 Dec 13;4(203):ra86</Citation><ArticleIdList><ArticleId IdType="pubmed">22169477</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2009 Jan 1;417(1):1-13</Citation><ArticleIdList><ArticleId IdType="pubmed">19061483</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Aspects Med. 1994;15 Suppl:s177-85</Citation><ArticleIdList><ArticleId IdType="pubmed">7752829</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Lett. 2002 May 28;131(3):191-4</Citation><ArticleIdList><ArticleId IdType="pubmed">11992738</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2950-5</Citation><ArticleIdList><ArticleId IdType="pubmed">17293453</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2014 Dec 20;21(18):2531-42</Citation><ArticleIdList><ArticleId IdType="pubmed">24766279</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 1998 Apr 21;37(16):5633-42</Citation><ArticleIdList><ArticleId IdType="pubmed">9548949</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2010 Aug 17;49(32):6963-9</Citation><ArticleIdList><ArticleId IdType="pubmed">20695533</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 1990 Dec 17;277(1-2):215-9</Citation><ArticleIdList><ArticleId IdType="pubmed">1702732</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2010 Jan;12(1):1-13</Citation><ArticleIdList><ArticleId IdType="pubmed">19852698</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Commun. 2013;4:1626</Citation><ArticleIdList><ArticleId IdType="pubmed">23535647</ArticleId></ArticleIdList></Reference><Reference><Citation>J Neurosci Res. 2006 Feb 1;83(2):256-63</Citation><ArticleIdList><ArticleId IdType="pubmed">16385584</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Med (Berl). 2012 Mar;90(3):233-44</Citation><ArticleIdList><ArticleId IdType="pubmed">22361849</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83</Citation><ArticleIdList><ArticleId IdType="pubmed">2352956</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7631-6</Citation><ArticleIdList><ArticleId IdType="pubmed">9636201</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2016 May 1;24(13):731-51</Citation><ArticleIdList><ArticleId IdType="pubmed">26607375</ArticleId></ArticleIdList></Reference><Reference><Citation>Free Radic Biol Med. 2008 Sep 1;45(5):549-61</Citation><ArticleIdList><ArticleId IdType="pubmed">18544350</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Res. 2006 Jul 1;66(13):6800-6</Citation><ArticleIdList><ArticleId IdType="pubmed">16818657</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2000 Jun 16;275(24):18121-8</Citation><ArticleIdList><ArticleId IdType="pubmed">10849437</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2004 Feb;6(1):63-74</Citation><ArticleIdList><ArticleId IdType="pubmed">14713336</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13398-403</Citation><ArticleIdList><ArticleId IdType="pubmed">23901112</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Portugal</li><li>République populaire de Chine</li><li>Suède</li></country><region><li>Svealand</li></region><settlement><li>Stockholm</li></settlement></list><tree><country name="Suède"><region name="Svealand"><name sortKey="Ren, Xiaoyuan" sort="Ren, Xiaoyuan" uniqKey="Ren X" first="Xiaoyuan" last="Ren">Xiaoyuan Ren</name></region><name sortKey="Holmgren, Arne" sort="Holmgren, Arne" uniqKey="Holmgren A" first="Arne" last="Holmgren">Arne Holmgren</name><name sortKey="Zhang, Xu" sort="Zhang, Xu" uniqKey="Zhang X" first="Xu" last="Zhang">Xu Zhang</name><name sortKey="Zou, Lili" sort="Zou, Lili" uniqKey="Zou L" first="Lili" last="Zou">Lili Zou</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Zou, Lili" sort="Zou, Lili" uniqKey="Zou L" first="Lili" last="Zou">Lili Zou</name></noRegion><name sortKey="Lu, Jun" sort="Lu, Jun" uniqKey="Lu J" first="Jun" last="Lu">Jun Lu</name><name sortKey="Wang, Jun" sort="Wang, Jun" uniqKey="Wang J" first="Jun" last="Wang">Jun Wang</name></country><country name="Portugal"><noRegion><name sortKey="Branco, Vasco" sort="Branco, Vasco" uniqKey="Branco V" first="Vasco" last="Branco">Vasco Branco</name></noRegion><name sortKey="Carvalho, Cristina" sort="Carvalho, Cristina" uniqKey="Carvalho C" first="Cristina" last="Carvalho">Cristina Carvalho</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/GlutaredoxinV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000321 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000321 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= GlutaredoxinV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28443683
|texte= Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28443683" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GlutaredoxinV1
| This area was generated with Dilib version V0.6.37. |  |